Ayalew Tefferi Selected Research

Systemic Mastocytosis

1/2022	Cladribine therapy for advanced and indolent systemic mastocytosis: Mayo Clinic experience in 42 consecutive cases.
1/2022	Midostaurin therapy for indolent and smoldering systemic mastocytosis: Retrospective review of Mayo Clinic experience.
1/2022	Midostaurin therapy for advanced systemic mastocytosis: Mayo Clinic experience in 33 consecutive cases.
3/2010	Systemic mastocytosis in adults: a review on prognosis and treatment based on 342 Mayo Clinic patients and current literature.
2/2010	Hypereosinophilic syndrome and clonal eosinophilia: point-of-care diagnostic algorithm and treatment update.
12/2009	Cytoreductive therapy in 108 adults with systemic mastocytosis: Outcome analysis and response prediction during treatment with interferon-alpha, hydroxyurea, imatinib mesylate or 2-chlorodeoxyadenosine.
6/2009	Systemic mastocytosis in 342 consecutive adults: survival studies and prognostic factors.
6/2008	Phase II study of dasatinib in Philadelphia chromosome-negative acute and chronic myeloid diseases, including systemic mastocytosis.
1/2008	KIT and mastocytosis.
8/2007	Kit: molecule of interest for the diagnosis and treatment of mastocytosis and other neoplastic disorders.

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Ayalew Tefferi Research Topics

Disease

123	Primary Myelofibrosis (Myelosclerosis) 01/2022 - 01/2002
81	Neoplasms (Cancer) 06/2022 - 02/2002
44	Polycythemia Vera 10/2018 - 04/2002
43	Anemia 01/2021 - 12/2002
40	Splenomegaly 10/2021 - 06/2002
38	Essential Thrombocythemia 01/2019 - 01/2004
30	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2022 - 08/2002
27	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2022 - 03/2003
26	Myeloproliferative Disorders (Myeloproliferative Disorder) 01/2021 - 01/2003
25	Leukemia 01/2022 - 01/2002
22	Systemic Mastocytosis 01/2022 - 11/2002
20	Thrombocytosis (Thrombocythemia) 01/2020 - 05/2002
19	Eosinophilia 01/2021 - 05/2002
18	Hematologic Neoplasms (Hematological Malignancy) 06/2022 - 02/2002
17	Thrombosis (Thrombus) 12/2021 - 05/2003
16	Thrombocytopenia (Thrombopenia) 11/2021 - 12/2002
16	Fibrosis (Cirrhosis) 01/2021 - 03/2002
15	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 10/2018 - 01/2002
13	Pruritus (Itching) 12/2021 - 04/2002
13	Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic) 11/2021 - 06/2004
13	Hypereosinophilic Syndrome (Loeffler Endocarditis) 02/2010 - 05/2002
11	Cytopenia 01/2022 - 01/2002
10	Pain (Aches) 01/2021 - 05/2004
10	Cachexia 01/2021 - 07/2004
9	Venous Thrombosis (Deep-Vein Thrombosis) 10/2022 - 06/2006
9	Leukocytosis (Pleocytosis) 01/2017 - 01/2003
8	Pdgfra-Associated Chronic Eosinophilic Leukemia 03/2010 - 06/2004
7	Chromosome Aberrations (Chromosome Abnormalities) 01/2022 - 03/2003
7	Polycythemia (Erythrocytosis) 12/2021 - 03/2005
6	Chronic Neutrophilic Leukemia 01/2021 - 08/2005
6	Portal Hypertension 11/2018 - 08/2005
6	Pulmonary Hypertension 12/2016 - 09/2002
5	Blast Crisis (Blast Phase) 01/2021 - 01/2018
5	Hemorrhage 01/2020 - 01/2004
5	Osteosclerosis 01/2006 - 01/2003
4	Abnormal Karyotype 01/2022 - 01/2012
4	Lymphoma (Lymphomas) 11/2020 - 01/2006
4	Neutropenia 02/2019 - 09/2008
4	Hepatomegaly 12/2016 - 02/2005
4	Mast Cell Activation Disorders (Mast-Cell Disease) 03/2010 - 01/2002
4	Immunoglobulin Light-chain Amyloidosis 02/2005 - 11/2002
3	Mast-Cell Leukemia (Leukemia, Mast Cell) 01/2022 - 01/2002

Drug/Important Bio-Agent (IBA)

32	Pharmaceutical PreparationsIBA 12/2021 - 05/2002
29	Hemoglobins (Hemoglobin)IBA 01/2022 - 12/2002
27	CytokinesIBA 01/2022 - 02/2002
22	Hydroxyurea (Hydrea)FDA LinkGeneric 12/2021 - 07/2003
22	Imatinib Mesylate (Gleevec)FDA Link 01/2018 - 01/2002
18	ruxolitinibIBA 01/2022 - 09/2009
15	Janus Kinase InhibitorsIBA 10/2021 - 09/2010
13	Janus Kinase 2IBA 01/2018 - 08/2005
13	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 02/2011 - 03/2003
12	Prednisone (Sone)FDA LinkGeneric 01/2021 - 03/2003
12	CalreticulinIBA 01/2019 - 08/2014
12	Erythropoietin FDA Link 11/2018 - 01/2003
12	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2017 - 02/2003
12	Platelet-Derived Growth Factor beta Receptor (Receptor, Platelet Derived Growth Factor beta)IBA 03/2016 - 11/2003
11	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 03/2003
11	Thalidomide (Thalomid)FDA Link 01/2021 - 05/2002
10	venetoclaxIBA 10/2022 - 11/2020
8	Reticulin (Reticular Fiber)IBA 01/2021 - 06/2002
8	Lenalidomide (CC 5013)FDA Link 01/2018 - 08/2006
8	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 02/2010 - 05/2003
7	Biological ProductsIBA 01/2021 - 01/2005
7	pomalidomideIBA 01/2021 - 09/2009
7	Adrenal Cortex Hormones (Corticosteroids)IBA 04/2014 - 01/2003
7	Phosphotransferases (Kinase)IBA 07/2011 - 01/2002
6	Cladribine FDA LinkGeneric 01/2022 - 03/2003
6	fedratinibIBA 01/2022 - 04/2008
6	CollagenIBA 01/2021 - 01/2003
6	Interferon-alpha (Interferon Alfa)IBA 01/2021 - 01/2005
6	AndrogensIBA 01/2021 - 01/2003
5	Biomarkers (Surrogate Marker)IBA 10/2022 - 10/2005
5	Busulfan (Busulfex)FDA Link 06/2022 - 04/2015
5	HematinicsIBA 01/2021 - 08/2009
5	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2016 - 07/2005
5	Indicators and Reagents (Reagents)IBA 12/2013 - 02/2005
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2022 - 06/2003
4	luspaterceptIBA 01/2022 - 01/2019
4	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2008
4	anagrelide (Agrylin)FDA LinkGeneric 01/2019 - 11/2004
4	Alkaline PhosphataseIBA 11/2018 - 11/2002
4	AnticoagulantsIBA 03/2013 - 08/2004
3	midostaurinIBA 01/2022 - 01/2020
3	CreatinineIBA 01/2022 - 08/2015
3	InterferonsIBA 12/2021 - 03/2004
3	Oxygen (Dioxygen)IBA 12/2021 - 05/2018
3	Decitabine FDA Link 01/2021 - 01/2019
3	Azacitidine (5 Azacytidine)FDA Link 01/2021 - 01/2019
3	imetelstatIBA 01/2021 - 09/2015
3	Danazol (Azol)FDA LinkGeneric 01/2021 - 01/2016

Therapy/Procedure

105	Therapeutics 01/2022 - 01/2002
20	Splenectomy 01/2021 - 09/2003
17	Drug Therapy (Chemotherapy) 01/2022 - 11/2002
13	Radiotherapy 01/2021 - 09/2002
8	Stem Cell Transplantation 01/2018 - 11/2002
5	Hematopoietic Stem Cell Transplantation 11/2020 - 05/2003
4	Induction Chemotherapy 10/2022 - 12/2007
4	Transplantation 10/2020 - 07/2004
4	Erythrocyte Transfusion 04/2014 - 07/2004
4	Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation) 11/2004 - 04/2003